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BRD4354
CAS No. 315698-07-8
BRD4354 ( BRD 4354 )
Catalog No. M14024 CAS No. 315698-07-8
BRD4354 is a moderately potent, selective, reversible inhibitor of HDAC5 and HDAC9 with IC50 of 0.85 uM and 1.88 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 35 | Get Quote |
|
| 5MG | 58 | Get Quote |
|
| 10MG | 102 | Get Quote |
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| 25MG | 205 | Get Quote |
|
| 50MG | 357 | Get Quote |
|
| 100MG | 530 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameBRD4354
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NoteResearch use only, not for human use.
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Brief DescriptionBRD4354 is a moderately potent, selective, reversible inhibitor of HDAC5 and HDAC9 with IC50 of 0.85 uM and 1.88 uM.
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DescriptionBRD4354 is a moderately potent, selective, reversible inhibitor of HDAC5 and HDAC9 with IC50 of 0.85 uM and 1.88 uM; shows weak activity against HDACs 4, 6, 7, and 8 (IC50=3.88-13.8 uM) and no inhibitory effect on other class I HDACs 1, 2, and 3 (IC50 > 40 uM).
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SynonymsBRD 4354
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PathwayCell Cycle/DNA Damage
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TargetHDAC
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RecptorHDAC
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Research Area——
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Indication——
Chemical Information
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CAS Number315698-07-8
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Formula Weight382.89
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Molecular FormulaC21H23ClN4O
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Purity>98% (HPLC)
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SolubilityDMSO : 125 mg/mL326.46 mM;
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SMILESOC1=C2N=CC=CC2=C(Cl)C=C1C(N3CCN(CC)CC3)C4=CC=CN=C4
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Chemical Name5-chloro-7-((4-ethylpiperazin-1-yl)(pyridin-3-yl)methyl)quinolin-8-ol
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Boskovic ZV, et al. ACS Chem Biol. 2016 Jul 15;11(7):1844-51.
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