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BPH-1358
CAS No. 5352-53-4
BPH-1358 ( NSC50460 )
Catalog No. M24517 CAS No. 5352-53-4
BPH-1358 (NSC50460) is a potent human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS) inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 272 | In Stock |
|
| 10MG | 408 | In Stock |
|
| 25MG | 612 | In Stock |
|
| 50MG | 918 | In Stock |
|
| 100MG | 1233 | In Stock |
|
| 500MG | 2457 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBPH-1358
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NoteResearch use only, not for human use.
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Brief DescriptionBPH-1358 (NSC50460) is a potent human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS) inhibitor.
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DescriptionBPH-1358 (NSC50460) is a potent human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS) inhibitor. With IC50s of 1.8 μM and 110 nM, respectively. And it is active against S. aureus in vitro (MIC ~250 ng/mL).
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SynonymsNSC50460
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PathwayOthers
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TargetOther Targets
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Recptorhuman bisphosphonate farnesyl diphosphate synthase
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Research Area——
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Indication——
Chemical Information
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CAS Number5352-53-4
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Formula Weight601.5
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Molecular FormulaC32H30Cl2N6O2
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(C1=CC=C(C2=CC=C(C(NC3=CC=CC(C4=NCCN4)=C3)=O)C=C2)C=C1)NC5=CC=CC(C6=NCCN6)=C5.[H]Cl.[H]Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Zhu W, et al. Antibacterial drug leads: DNA and enzyme multitargeting. J Med Chem. 2015 Feb 12;58(3):1215-27.
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