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BMS986299
CAS No. 2242952-69-6
BMS986299( Unii-VS58MO4P47 )
Catalog No. M28769 CAS No. 2242952-69-6
BMS986299 is a modulator of NLRP3 with an EC50 of 1.28 μM and can be used in studies about NLRP3 signaling and the treatment of associated diseases.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 87 | Get Quote |
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| 10MG | 155 | Get Quote |
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| 25MG | 327 | Get Quote |
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| 50MG | 520 | Get Quote |
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| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameBMS986299
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NoteResearch use only, not for human use.
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Brief DescriptionBMS986299 is a modulator of NLRP3 with an EC50 of 1.28 μM and can be used in studies about NLRP3 signaling and the treatment of associated diseases.
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DescriptionBMS986299 is a modulator of NLRP3 with an EC50 of 1.28 μM and can be used in studies about NLRP3 signaling and the treatment of associated diseases.
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In Vitro——
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In Vivo——
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SynonymsUnii-VS58MO4P47
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PathwayNF-κB
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TargetNOD
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RecptorCationic Lipid
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Research Area——
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Indication——
Chemical Information
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CAS Number2242952-69-6
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Formula Weight349.39
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Molecular FormulaC18H19N7O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 33.33 mg/mL (95.39 mM)
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SMILESO=C(N(CC1=NC=2C(=NC=3C=C(C=CC3C2N1)C4=NNC=C4)N)CC)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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NLRP3-IN-9
NLRP3-IN-9 is an inhibitor of NLRP3 ATPase and caspase-1. NLRP3-IN-9 acts by irreversibly trapping thiol nucleophiles, which prevents both ATP- and nigericin-triggered pyroptosis of human THP-1 cells in a time- and concentration-dependent manner.
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Lobeglitazone Sulfat...
Lobeglitazone Sulfate（CKD-501 Sulfate） is a novel thiazolidinedione with anti-inflammatory activity that inhibits LPS-induced NLRP3 inflammasome activation and hepatic inflammation, and can be used in the study of type 2 diabetes mellitus (T2DM).
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ADS032
ADS032 (BT-032) is an NLRP1 and NLRP3 inhibitor with anti-inflammatory activity,, inhibits the activation of NLRP1 and NLRP3, inhibits Nigericin-induced IL-1β production, and can be used to study respiratory inflammation or infection.
