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BMS-961955
CAS No. 1431328-92-5
BMS-961955( BMS961955 )
Catalog No. M11828 CAS No. 1431328-92-5
BMS-961955 is an potent, allosteric inhibitor of HCV NS5B polymerase with EC50 of 7.9/4.3 nM for GT 1b/1a replicon respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 1773 | Get Quote |
|
| 50MG | 3582 | Get Quote |
|
| 100MG | 4950 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameBMS-961955
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NoteResearch use only, not for human use.
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Brief DescriptionBMS-961955 is an potent, allosteric inhibitor of HCV NS5B polymerase with EC50 of 7.9/4.3 nM for GT 1b/1a replicon respectively.
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DescriptionBMS-961955 is an potent, allosteric inhibitor of HCV NS5B polymerase with EC50 of 7.9/4.3 nM for GT 1b/1a replicon respectively; shows weak activity against PXR; displayes significantly enhanced metabolic stability in CLM and HLM.
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In Vitro——
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In Vivo——
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SynonymsBMS961955
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PathwayMicrobiology/Virology
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TargetHCV
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RecptorHCV
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Research AreaInfection
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Indication——
Chemical Information
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CAS Number1431328-92-5
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Formula Weight658.833
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Molecular FormulaC37H43FN4O4S
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Purity>98% (HPLC)
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Solubility——
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SMILESCC1(CC1)S(=O)(=O)NC(=O)C2=CC3=C(C=C2)C(=C4N3CC5(CC5C6=C4C=CC(=C6)F)C(=O)N7C8CCC7CN(C8)C)C9CCCCC9
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Chemical Name(4bS,5aR)-12-Cyclohexyl-3-fluoro-4b,5,5a,6-tetrahydro-N-[(1-methylcyclopropyl)sulfonyl]-5a-[(3-methyl-3,8-diazabicyclo[3.2.1]oct-8-yl)carbonyl]cycloprop[d]indolo[2,1-a][2]benzazepine-9-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Zheng BZ, et al. Bioorg Med Chem Lett. 2017 Jun 11. pii: S0960-894X(17)30626-1.
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