BMS-265246

CAS No. 582315-72-8

BMS-265246 ( BMS265246; BMS-265246; BMS 265246 )

Catalog No. M15136 CAS No. 582315-72-8

BMS-265246 is a potent and selective CDK1/2 inhibitor with IC50 of 6 nM/9 nM in a cell-free assay.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 102 Get Quote
10MG 177 Get Quote
25MG 350 Get Quote
50MG 530 Get Quote
100MG 759 Get Quote
500MG 1557 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    BMS-265246
  • Note
    Research use only, not for human use.
  • Brief Description
    BMS-265246 is a potent and selective CDK1/2 inhibitor with IC50 of 6 nM/9 nM in a cell-free assay.
  • Description
    BMS-265246 is a potent and selective CDK1/2 inhibitor with IC50 of 6 nM/9 nM in a cell-free assay. It is 25-fold more selective for CDK1/2 than CDK4.
  • Synonyms
    BMS265246; BMS-265246; BMS 265246
  • Pathway
    Angiogenesis
  • Target
    CDK
  • Recptor
    CDK1/CyclinB; CDK2/CyclinE; CDK4/CyclinD
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    582315-72-8
  • Formula Weight
    345.34
  • Molecular Formula
    C18H17F2N3O2
  • Purity
    >98%(HPLC)
  • Solubility
    DMSO: 20 mg/mL (57.91 mM)
  • SMILES
    O=C(C1=CN=C(NN=C2)C2=C1OCCCC)C3=C(F)C=C(C)C=C3F
  • Chemical Name
    (4-butoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)(2,6-difluoro-4-methylphenyl)methanone

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Misra RN, et al. Bioorg Med Chem Lett. 2003, 13(14), 2405-2408.
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