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BMS-265246
CAS No. 582315-72-8
BMS-265246 ( BMS265246; BMS-265246; BMS 265246 )
Catalog No. M15136 CAS No. 582315-72-8
BMS-265246 is a potent and selective CDK1/2 inhibitor with IC50 of 6 nM/9 nM in a cell-free assay.
Purity : >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 102 | Get Quote |
|
| 10MG | 177 | Get Quote |
|
| 25MG | 350 | Get Quote |
|
| 50MG | 530 | Get Quote |
|
| 100MG | 759 | Get Quote |
|
| 500MG | 1557 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameBMS-265246
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NoteResearch use only, not for human use.
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Brief DescriptionBMS-265246 is a potent and selective CDK1/2 inhibitor with IC50 of 6 nM/9 nM in a cell-free assay.
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DescriptionBMS-265246 is a potent and selective CDK1/2 inhibitor with IC50 of 6 nM/9 nM in a cell-free assay. It is 25-fold more selective for CDK1/2 than CDK4.
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SynonymsBMS265246; BMS-265246; BMS 265246
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PathwayAngiogenesis
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TargetCDK
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RecptorCDK1/CyclinB; CDK2/CyclinE; CDK4/CyclinD
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number582315-72-8
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Formula Weight345.34
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Molecular FormulaC18H17F2N3O2
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Purity>98%(HPLC)
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SolubilityDMSO: 20 mg/mL (57.91 mM)
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SMILESO=C(C1=CN=C(NN=C2)C2=C1OCCCC)C3=C(F)C=C(C)C=C3F
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Chemical Name(4-butoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)(2,6-difluoro-4-methylphenyl)methanone
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Misra RN, et al. Bioorg Med Chem Lett. 2003, 13(14), 2405-2408.
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