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BIO-013077-01
CAS No. 746667-48-1
BIO-013077-01( —— )
Catalog No. M21624 CAS No. 746667-48-1
BIO-013077-01 is a potent TGFbeta family type I receptors antagonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 140 | Get Quote |
|
| 10MG | 215 | Get Quote |
|
| 25MG | 430 | Get Quote |
|
| 50MG | 621 | Get Quote |
|
| 100MG | 879 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameBIO-013077-01
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NoteResearch use only, not for human use.
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Brief DescriptionBIO-013077-01 is a potent TGFbeta family type I receptors antagonist.
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DescriptionBIO-013077-01 is a potent TGFbeta family type I receptors antagonist.
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In VitroA wide range of cellular functions such as cell proliferation, differentiation, adhesion, migration, and apoptosis are regulated by TGF-β superfamily members. The TGF-βs include the three major TGF-β isoforms, TGF-β1, TGF-β2, and TGF-β3 which are expressed in mammals. TGF-β transduces signals through a complex of two related but structurally and functionally distinct serine/threonine kinase receptors, termed type 1 and type II. Deregulation of TGF-β signaling has been also implicated in various human diseases including cancer, pancreatic diseases, and hematological malignancies.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorTGFβ
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Research Area——
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Indication——
Chemical Information
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CAS Number746667-48-1
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Formula Weight287.32
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Molecular FormulaC17H13N5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (348.04 mM)
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SMILESCc1cccc(n1)-c1n[nH]cc1-c1ccc2nccnc2c1
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Chemical Name6-[3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl]quinoxaline
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Koike R Uchiyama T Arimoto-Kobayashi S Okamoto K Negishi T. Increase of somatic cell mutations in oxidative damage-sensitive drosophila. Genes Environ. 2018 Jan 10;40:3.
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