Cart
sales@molnova.com
BIBF0775
CAS No. 334951-90-5
BIBF0775( —— )
Catalog No. M20053 CAS No. 334951-90-5
BIBF0775 is a selective TGFβ type I receptor (Alk5) inhibitor (IC50: 34 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 132 | In Stock |
|
| 10MG | 205 | In Stock |
|
| 25MG | 340 | In Stock |
|
| 50MG | 478 | In Stock |
|
| 100MG | 691 | In Stock |
|
| 500MG | 1422 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameBIBF0775
-
NoteResearch use only, not for human use.
-
Brief DescriptionBIBF0775 is a selective TGFβ type I receptor (Alk5) inhibitor (IC50: 34 nM).
-
DescriptionBIBF0775 is a selective TGFβ type I receptor (Alk5) inhibitor (IC50: 34 nM).
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorTGFβR1(ALK5)|Alk5
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number334951-90-5
-
Formula Weight494.64
-
Molecular FormulaC31H34N4O2
-
Purity>98% (HPLC)
-
SolubilityDMSO: 60 mg/mL
-
SMILESCCN(C)C(=O)c1ccc2c(NC(=O)\C2=C(/Nc2ccc(CN3CCCCC3)cc2)c2ccccc2)c1
-
Chemical Name(3Z)-N-Ethyl-23-dihydro-N-methyl-2-oxo-3-[phenyl[[4-(1-piperidinylmethyl)phenyl]amino]methylene]-1H-indole-6-carboxamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Roth GJ et al. Design synthesis and evaluation of indolinones as inhibitors of the transforming growth factor β receptor I (TGFβRI). J Med Chem. 2010 Oct 28;53(20):7287-95.
molnova catalog
related products
-
Danshenxinkun A
Danshenxinkun A, Danshenxinkun B and Neocryptotanshinone may intervene thrombotic diseases by adjusting the targets mainly involved in pathways of endocrine system, signal transduction, signaling molecules and interaction, cell motility, environmental adaptation and nervous system.
-
1,16-Hexadecanediol
1,16-Hexadecanediol has low toxicity and can be used to make resins and nanomaterials.
-
Apelin-13 TFA (21708...
Apelin-13 is an endogenous ligand of APJ receptor, and the EC 50 value of activated G protein coupled receptor is 0.37 nM.
