BIBF0775

CAS No. 334951-90-5

BIBF0775 ( —— )

Catalog No. M20053 CAS No. 334951-90-5

BIBF0775 is a selective TGFβ type I receptor (Alk5) inhibitor (IC50: 34 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 132 In Stock
10MG 205 In Stock
25MG 340 In Stock
50MG 478 In Stock
100MG 691 In Stock
500MG 1422 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    BIBF0775
  • Note
    Research use only not for human use.
  • Brief Description
    BIBF0775 is a selective TGFβ type I receptor (Alk5) inhibitor (IC50: 34 nM).
  • Description
    BIBF0775 is a selective TGFβ type I receptor (Alk5) inhibitor (IC50: 34 nM).
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    TGFβR1(ALK5);Alk5
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    334951-90-5
  • Formula Weight
    494.64
  • Molecular Formula
    C31H34N4O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 60 mg/mL
  • SMILES
    CCN(C)C(=O)c1ccc2c(NC(=O)\C2=C(/Nc2ccc(CN3CCCCC3)cc2)c2ccccc2)c1
  • Chemical Name
    (3Z)-N-Ethyl-23-dihydro-N-methyl-2-oxo-3-[phenyl[[4-(1-piperidinylmethyl)phenyl]amino]methylene]-1H-indole-6-carboxamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Roth GJ et al. Design synthesis and evaluation of indolinones as inhibitors of the transforming growth factor β receptor I (TGFβRI). J Med Chem. 2010 Oct 28;53(20):7287-95.
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