Cart
sales@molnova.com
BI-4464
CAS No. 1227948-02-8
BI-4464( —— )
Catalog No. M20216 CAS No. 1227948-02-8
BI-4464 is a highly selective ATP competitive inhibitor of?PTK2/FAK with an?IC50?of 17 nM. A PTK2 ligand for PROTAC.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 77 | In Stock |
|
| 5MG | 132 | In Stock |
|
| 10MG | 215 | In Stock |
|
| 25MG | 356 | In Stock |
|
| 50MG | 530 | In Stock |
|
| 100MG | 772 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameBI-4464
-
NoteResearch use only, not for human use.
-
Brief DescriptionBI-4464 is a highly selective ATP competitive inhibitor of?PTK2/FAK with an?IC50?of 17 nM. A PTK2 ligand for PROTAC.
-
DescriptionBI-4464 is a highly selective ATP competitive inhibitor of?PTK2/FAK with an?IC50?of 17 nM. A PTK2 ligand for PROTAC.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayAngiogenesis
-
TargetFAK
-
RecptorPTK2/FAK
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1227948-02-8
-
Formula Weight555.56
-
Molecular FormulaC28H28F3N5O4
-
Purity>98% (HPLC)
-
SolubilityDMSO:16.67 mg/mL?(30.01 mM)
-
SMILESCOc1cc(ccc1Nc1ncc(c(Oc2cccc3CCC(=O)c23)n1)C(F)(F)F)C(=O)NC1CCN(C)CC1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Popow J et al. Highly Selective PTK2 Proteolysis Targeting Chimeras to Probe Focal Adhesion Kinase Scaffolding Functions. J Med Chem. 2019 Mar 14;62(5):2508-2520.
molnova catalog
related products
-
Y15
Y15 is a potent and specificsmall-molecule FAK scaffolding inhibitor that inhibits its autophosphorylation activity blocks tumor growth.
-
PF-562271 HCl
PF-562271 is a potent ATP-competitive reversible inhibitor of FAK with IC50 of 1.5 nM in cell-free assays.
-
ALK inhibitor 1
ALK inhibitor 1 is a selective ALK kinase inhibitor.
