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BI-2493

CAS No. 2937344-16-4

BI-2493( —— )

Catalog No. M36424 CAS No. 2937344-16-4

BI-2493 is a highly selective pan-KRAS inhibitor and structural analog of BI-2865.BI-2493 exhibits antitumor activity and inhibits tumor cell growth and can be used in the study of cancerous diseases.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    BI-2493
  • Note
    Research use only, not for human use.
  • Brief Description
    BI-2493 is a highly selective pan-KRAS inhibitor and structural analog of BI-2865.BI-2493 exhibits antitumor activity and inhibits tumor cell growth and can be used in the study of cancerous diseases.
  • Description
    BI-2493 is a structural analogue of BI-2865 and a highly selective pan-KRAS inhibitor. BI-2493 can attenuate tumor growth. BI-2493 can be used for cancer iseases research.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Kras
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2937344-16-4
  • Formula Weight
    461.58
  • Molecular Formula
    C24H27N7OS
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (108.32 mM; Ultrasonic )
  • SMILES
    C(#N)C=1C=2[C@@]3(C4=C(C(=NO4)C5=NC(=NC=C5)N6[C@@H](C)CNCC6)CCC3)CCCC2SC1N
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kim D, et al. Pan-KRAS inhibitor disables oncogenic signalling and tumour growth. Nature. 2023 Jul;619(7968):160-166.?
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