
BGP-15
CAS No. 66611-37-8
BGP-15( BGP 15 | BGP15 )
Catalog No. M15540 CAS No. 66611-37-8
A PARP inhibitor and an inducer of HSF-1/HSP72 (cotreatment with heat) in vtiro.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
2MG | 34 | In Stock |
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5MG | 55 | In Stock |
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10MG | 91 | In Stock |
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25MG | 178 | In Stock |
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50MG | 332 | In Stock |
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100MG | 431 | In Stock |
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200MG | Get Quote | In Stock |
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500MG | Get Quote | In Stock |
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1G | Get Quote | In Stock |
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Biological Information
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Product NameBGP-15
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NoteResearch use only, not for human use.
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Brief DescriptionA PARP inhibitor and an inducer of HSF-1/HSP72 (cotreatment with heat) in vtiro.
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DescriptionA PARP inhibitor and an inducer of HSF-1/HSP72 (cotreatment with heat) in vtiro; has no effect on HSP90 levels, markedly increases the phosphorylation of HSF1 and expression of HSF1 and HSP72 in adipocytes and muscle cells; protects against obesity-induced insulin resistance and orally active; alleviates ventilation-induced diaphragm dysfunction associated with HSP72 induction and PARP-1 inhibition.Diabetes Phase 2 Clinical.
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In Vitro——
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In Vivo——
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SynonymsBGP 15 | BGP15
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PathwayCell Cycle/DNA Damage
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TargetPARP
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RecptorPARP
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Research AreaMetabolic Disease
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IndicationDiabetes
Chemical Information
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CAS Number66611-37-8
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Formula Weight351.272
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Molecular FormulaC14H24Cl2N4O2
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Purity>98% (HPLC)
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SolubilityDMSO: 11.33 mg/mL
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SMILESC1CCN(CC1)CC(CON=C(C2=CN=CC=C2)N)O.Cl.Cl
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Chemical Name3-Pyridinecarboximidamide, N-[2-hydroxy-3-(1-piperidinyl)propoxy]-, hydrochloride (1:2)
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Salah H, et al. Sci Transl Med. 2016 Aug 3;8(350):350ra103.
2. Chung J, et al. Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1739-44.
3. Racz I, et al. Biochem Pharmacol. 2002 Mar 15;63(6):1099-111.
4. Kardon T, et al. Anticancer Res. 2006 Mar-Apr;26(2A):1023-8.
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BGP-15
A PARP inhibitor and an inducer of HSF-1/HSP72 (cotreatment with heat) in vtiro.