BCI

CAS No. 1245792-51-1

BCI ( (E)-BCI )

Catalog No. M22447 CAS No. 1245792-51-1

BCI is an allosteric inhibitor of dual-specificity phosphatase (DUSP; EC50s: 13.3 and 8.0 μM for DUSP6 and DUSP1 in cells) and does not inhibit DUSP5.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 113 In Stock
10MG 186 In Stock
25MG 298 In Stock
50MG 447 In Stock
100MG 651 In Stock
500MG 1368 In Stock
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Biological Information

  • Product Name
    BCI
  • Note
    Research use only, not for human use.
  • Brief Description
    BCI is an allosteric inhibitor of dual-specificity phosphatase (DUSP; EC50s: 13.3 and 8.0 μM for DUSP6 and DUSP1 in cells) and does not inhibit DUSP5.
  • Description
    BCI is an allosteric inhibitor of dual-specificity phosphatase (DUSP; EC50s: 13.3 and 8.0 μM for DUSP6 and DUSP1 in cells) and does not inhibit DUSP5.
  • Synonyms
    (E)-BCI
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Phosphatase
  • Recptor
    phosphatase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1245792-51-1
  • Formula Weight
    317.42
  • Molecular Formula
    C22H23NO
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:125 mg/mL (393.80 mM; Need ultrasonic)
  • SMILES
    O=C1c2ccccc2C(NC2CCCCC2)\C1=C/c1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Korotchenko VN, et al. In vivo structure-activity relationship studies support allosteric targeting of a dual specificity phosphatase. Chembiochem. 2014 Jul 7;15(10):1436-45.
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