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BC1618

CAS No. 2222094-18-8

BC1618 ( 2-Propanol, 1-[bis(phenylmethyl)amino]-3-[4-(trifluoromethyl)phenoxy]- )

Catalog No. M24005 CAS No. 2222094-18-8

BC1618 is an orally active Fbxo48 inhibitory compound, stimulates Ampk-dependent signaling.

Purity : >98% (HPLC)

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Size	Price / USD	Stock	Quantity
5MG	68	In Stock
10MG	110	In Stock
25MG	222	In Stock
50MG	380	In Stock
100MG	565	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

BC1618
Note

Research use only, not for human use.
Brief Description

BC1618 is an orally active Fbxo48 inhibitory compound, stimulates Ampk-dependent signaling.
Description

BC1618 is an orally active Fbxo48 inhibitory compound, stimulates Ampk-dependent signaling. It promotes mitochondrial fission, facilitates autophagy and improves hepatic insulin sensitivity.
Synonyms

2-Propanol, 1-[bis(phenylmethyl)amino]-3-[4-(trifluoromethyl)phenoxy]-
Pathway

Membrane Transporter/Ion Channel
Target

AMPK
Recptor

AMPK;E1/E2/E3 Enzyme;Fbxo48;Mitophagy
Research Area

——
Indication

——

Chemical Information

CAS Number

2222094-18-8
Formula Weight

415.5
Molecular Formula

C24H24F3NO2
Purity

>98% (HPLC)
Solubility

DMSO:100 mg/mL?(240.70 mM;?Need ultrasonic)
SMILES

OC(COC1=CC=C(C(F)(F)F)C=C1)CN(CC2=CC=CC=C2)CC3=CC=CC=C3
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Yuan Liu, et al. A Fbxo48 inhibitor prevents pAMPKα degradation and ameliorates insulin resistance. Nat Chem Biol. 2021 Mar;17(3):298-306.

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