B220

CAS No. 112228-65-6

B220( —— )

Catalog No. M26068 CAS No. 112228-65-6

B220, an antiviral agent, inhibits the growth of HSV-1, HSV-2, and human cytomegalovirus (CMV).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 888 Get Quote
25MG 1341 Get Quote
50MG 1782 Get Quote
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Biological Information

  • Product Name
    B220
  • Note
    Research use only, not for human use.
  • Brief Description
    B220, an antiviral agent, inhibits the growth of HSV-1, HSV-2, and human cytomegalovirus (CMV).
  • Description
    B220, an antiviral agent, inhibits the growth of HSV-1, HSV-2, and human cytomegalovirus (CMV).(In Vitro):B220 inhibits the neutrophil release of reactive oxygen species, as well as the intracellular generation of reactive oxygen species. The inhibition is not achieved through direct oxygen radical scavenger activity of B220, and B220 has no immediate effects on the activity of the assembled oxidase. The neutrophil capability to phagocytose fluorescein-labeled opsonized yeast cells is reduced by B220. Cells preincubated with B220 (10 μg/mL) and then stimulated with the formylated peptide fMLP mobilize fewer C3 receptors on their surface than the control cells .
  • In Vitro
    B220 is an antiviral agent which can inhibit the growth of HSV-1, HSV-2 and human cytomegalovirus (CMV). B220 inhibits neutrophil release of reactive oxygen species, as well as intracellular generation of reactive oxygen species. The inhibition is not achieved through direct oxygen radical scavenger activity of B220, and B220 has no immediate effects on the activity of the assembled oxidase. The neutrophil capability to phagocytose fluorescein-labeled opsonized yeast cells is reduced by B220. Cells preincubated with B220 (10 μg/mL) and then stimulated with the formylated peptide fMLP mobilize fewer C3 receptors on their surface than the control cells.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    HSV
  • Recptor
    SK?channels
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    112228-65-6
  • Formula Weight
    318.424
  • Molecular Formula
    C20H22N4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CN(C)CCn1c2ccccc2c2nc3cc(C)c(C)cc3nc12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Crystalline forms of potassium channel modulators. WO2020086456A1.
molnova catalog
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