Azide-PEG3-Desthiobiotin

CAS No. 1426828-06-9

Azide-PEG3-Desthiobiotin( —— )

Catalog No. M35075 CAS No. 1426828-06-9

Azide-PEG3-Desthiobiotin is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 47 Get Quote
5MG 68 Get Quote
10MG 116 Get Quote
25MG 250 Get Quote
50MG 403 Get Quote
100MG 592 Get Quote
500MG 1242 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Azide-PEG3-Desthiobiotin
  • Note
    Research use only, not for human use.
  • Brief Description
    Azide-PEG3-Desthiobiotin is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules.
  • Description
    Azide-PEG3-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azide-PEG3-Desthiobiotin is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
  • In Vitro
    PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1426828-06-9
  • Formula Weight
    414.5
  • Molecular Formula
    C18H34N6O5
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(CCCCC(NCCOCCOCCOCCN=[N+]=[N-])=O)[C@@H]1[C@H](C)NC(=O)N1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562?
molnova catalog
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