Azaserine

Research use only, not for human use.

Azaserine is a tumor-inhibiting antibiotic isolated from a species of Streptomyces and functions as an inhibitor of glutamine amidotransferase.

Azaserine is a tumor-inhibiting antibiotic isolated from a species of Streptomyces and functions as an inhibitor of glutamine amidotransferase.(In Vitro):Azaserine inhibits the hexosamine biosynthetic pathway, which shunts excessive intracellular glucose into the biosynthesis of UDP-N-acetylglucosamine and the formation of O-linked glycoproteins . Azaserine (25 μM) inhibits the glutamine-dependent amidotransferases involved in nucleotide biosynthesis, phosphoribosylformylglycinamidine synthetase, and glucosamine-6-phosphate isomerase.

CI-337; O-Diazoacetyl-L-serine; P-165

Others

Other Targets

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115-02-6

173.1

C5H7N3O4

>98% (HPLC)

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N[C@@H](COC(=O)C=[N+]=[N-])C(O)=O

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(-20℃)

With Ice Pack

≥ 2 years