Auxinole ( —— )

Catalog No. M24866 CAS No. 86445-22-9

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Auxinole
Note

Research use only, not for human use.
Brief Description

Auxinole is a potent auxin antagonist of TIR1/AFB receptors, binding TIR1 to block the formation of the TIR1-IAA-Aux/IAA complex . It inhibits auxin-responsive gene expression.
Description

Auxinole is a potent auxin antagonist of TIR1/AFB receptors, binding TIR1 to block the formation of the TIR1-IAA-Aux/IAA complex . It inhibits auxin-responsive gene expression.
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

TIR1/AFB receptor
Research Area

——
Indication

——

CAS Number

86445-22-9
Formula Weight

321.4
Molecular Formula

C20H19NO3
Purity

>98% (HPLC)
Solubility

DMSO:125 mg/mL (388.96 mM);Ethanol:12.5 mg/mL (38.90 mM; Need ultrasonic)
SMILES

Cc(cc1)cc(C)c1C(CC(C(O)=O)c1c[nH]c2c1cccc2)=O
Chemical Name

——

1.Hayashi K, et al. Rational design of an auxin antagonist of the SCF(TIR1) auxin receptor complex. ACS Chem Biol. 2012 Mar 16;7(3):590-8.

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