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Aurantiamide
CAS No. 58115-31-4
Aurantiamide( TMC-58B )
Catalog No. M20469 CAS No. 58115-31-4
Aurantiamide has anti-cancer anti-inflammatory and antinociceptive activities it may suppress the growth of malignant gliomas by blocking autophagic flux.Aurantiamide has an anti-neuroinflammatory effect on LPS stimulation through its inhibition of the NF-κB JNK and p38 pathways.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 374 | In Stock |
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| 10MG | 556 | In Stock |
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| 25MG | 887 | In Stock |
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| 50MG | 1197 | In Stock |
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| 100MG | 1611 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameAurantiamide
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NoteResearch use only, not for human use.
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Brief DescriptionAurantiamide has anti-cancer anti-inflammatory and antinociceptive activities it may suppress the growth of malignant gliomas by blocking autophagic flux.Aurantiamide has an anti-neuroinflammatory effect on LPS stimulation through its inhibition of the NF-κB JNK and p38 pathways.
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DescriptionAurantiamide has anti-cancer anti-inflammatory and antinociceptive activities it may suppress the growth of malignant gliomas by blocking autophagic flux.Aurantiamide has an anti-neuroinflammatory effect on LPS stimulation through its inhibition of the NF-κB JNK and p38 pathways.
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In Vitro——
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In Vivo——
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SynonymsTMC-58B
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PathwayApoptosis
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TargetNF-κB
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RecptorNF-κB|p38
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Research Area——
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Indication——
Chemical Information
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CAS Number58115-31-4
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Formula Weight402.5
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Molecular FormulaC25H26N2O3?
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Purity>98% (HPLC)
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Solubility——
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SMILESOC[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccccc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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CL075
CL075 (3M002) is a selective TLR8 agonist with immunomodulatory activity, triggering the MyD88-dependent signaling pathway and activating NF-κB and IRF7 to elicit the production of inflammatory cytokines and type I interferon (IFN).
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Urolithin B
Urolithin B inhibits NF-κB activity by reducing the phosphorylation and degradation of IκBα, and suppresses the phosphorylation of JNK, ERK, and Akt, and enhances the phosphorylation of AMPK.?Urolithin B is also a regulator of skeletal muscle mass.Urolithin B is one of the gut microbial metabolites of ellagitannins, and has anti-inflammatory and antioxidant effects.
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Methylene Blue
Methylene Blue(IC50 of 1.9 μM) inhibits tau filament formation. And it inhibits soluble guanylyl cyclase. It is also used as a dye in chromoendoscopy.
