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Asperphenamate

CAS No. 63631-36-7

Asperphenamate( —— )

Catalog No. M32791 CAS No. 63631-36-7

Asperphenamate is a fungal metabolite of Aspergillus flatiipes. The IC50s for T47D cells, MDA-MB-231 cells, and HL-60 cells are 92.3 μM, 96.5 μM, and 97.9 μM.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    Asperphenamate
  • Note
    Research use only, not for human use.
  • Brief Description
    Asperphenamate is a fungal metabolite of Aspergillus flatiipes. The IC50s for T47D cells, MDA-MB-231 cells, and HL-60 cells are 92.3 μM, 96.5 μM, and 97.9 μM.
  • Description
    Asperphenamate, a fungal metabolite of Aspergillus flatiipes with anti-cancer effect, exhibits IC50 values of 92.3 μM, 96.5 μM and 97.9 μM in T47D, MDA-MB-231 and HL-60 cells, respectively.
  • In Vitro
    Asperphenamate can inhibit cancer cell proliferation by fully inducing autophagy. asperphenamate showed inhibition effects against cathepsin L. At the same time, it also displayed weak inhibitory ability against cathepsin S.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    Antifungal
  • Recptor
    Antifungal
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    63631-36-7
  • Formula Weight
    506.59
  • Molecular Formula
    C32H30N2O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (197.40 mM; Ultrasonic )
  • SMILES
    O=C(OC[C@H](Cc1ccccc1)NC(=O)c1ccccc1)[C@H](Cc1ccccc1)NC(=O)c1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Alice M.Clark, et al. Synthesis of asperphenamate, a novel fungal metabolite. Phytochemistry
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