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Asenapine

CAS No. 65576-45-6

Asenapine ( Org 5222;Org-5222;Org5222 )

Catalog No. M15492 CAS No. 65576-45-6

A potent psychopharmacologic agent that shows high affinity for 5-HT, dopamine, histamine and adrenoceptors.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    Asenapine
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent psychopharmacologic agent that shows high affinity for 5-HT, dopamine, histamine and adrenoceptors.
  • Description
    A potent psychopharmacologic agent that shows high affinity for 5-HT, dopamine, histamine and adrenoceptors; shows much lower affinity (pKi<5) for muscarinic receptor; behaves as a potent antagonist 5-HT receptors (5-HT2A pKB=9.0), dopaime and adrenoceptors; shows strong antipsychotic potential in vivo.SchizophreniaApproved
  • Synonyms
    Org 5222;Org-5222;Org5222
  • Pathway
    Angiogenesis
  • Target
    Adrenergic Receptor
  • Recptor
    Adrenergic Receptor
  • Research Area
    Neurological Disease
  • Indication
    Schizophrenia

Chemical Information

  • CAS Number
    65576-45-6
  • Formula Weight
    285.77
  • Molecular Formula
    C17H16ClNO
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    CN1CC2C(C1)C3=C(C=CC(=C3)Cl)OC4=CC=CC=C24
  • Chemical Name
    1H-Dibenz[2,3:6,7]oxepino[4,5-c]pyrrole, 5-chloro-2,3,3a,12b-tetrahydro-2-methyl-, (3aR,12bR)-rel-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Room P, et al. Eur J Pharmacol. 1991 Dec 3;205(3):233-40.
2. Broekkamp CL, et al. Arzneimittelforschung. 1990 May;40(5):544-9.
3. Frnberg O, et al. Psychopharmacology (Berl). 2008 Feb;196(3):417-29.
4. Shahid M, et al. J Psychopharmacol. 2009 Jan;23(1):65-73.
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