Ascomycin

CAS No. 104987-12-4

Ascomycin ( FK-520; FR900520; L-683590; Changchuanmycin )

Catalog No. M17780 CAS No. 104987-12-4

Ascomycin(Immunomycin, FR-900520, FK520) is an ethyl analog of tacrolimus (FK506) with strong immunosuppressant properties.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 32 In Stock
10MG 47 In Stock
50MG 57 In Stock
100MG 73 In Stock
200MG Get Quote In Stock
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Biological Information

  • Product Name
    Ascomycin
  • Note
    Research use only, not for human use.
  • Brief Description
    Ascomycin(Immunomycin, FR-900520, FK520) is an ethyl analog of tacrolimus (FK506) with strong immunosuppressant properties.
  • Description
    Ascomycin, also known as KF-520, FR900520, L 683590, produced by the fermentation of S. hygroscopicus subsp. ascomyceticus, is an ethyl analog of tacrolimus (FK-506) with potent immunosuppressant properties.
  • Synonyms
    FK-520; FR900520; L-683590; Changchuanmycin
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    calcineurin phosphatase
  • Research Area
    Infection
  • Indication
    ——

Chemical Information

  • CAS Number
    104987-12-4
  • Formula Weight
    792.01
  • Molecular Formula
    C43H69NO12
  • Purity
    98%
  • Solubility
    DMSO : ≥ 39 mg/mL; 49.24 mM
  • SMILES
    O1[C@@]2(O)C(=O)C(=O)N3[C@H](C(=O)O[C@@H]([C@@H]([C@@H](O)CC(=O)[C@@H](/C=C(/C[C@@H](C[C@H](OC)[C@@H]1[C@@H](OC)C[C@H]2C)C)\C)CC)C)/C(=C/[C@H]1C[C@@H](OC)[C@H](O)CC1)/C)CCCC3
  • Chemical Name
    (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-8-ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hatanaka H, et al. J Antibiot (Tokyo). 1988, 41(11), 1592-1601.
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