Artesunate ( Artesunic Acid; NSC 712571; WR 256283 )

Catalog No. M16406 CAS No. 88495-63-0

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Product Name

Artesunate
Note

Research use only, not for human use.
Brief Description

Artesunate is a part of the artemisinin group of agents with an IC50 of < 5 μM for small cell lung carcinoma cell line H69.
Description

Artesunate is a part of the artemisinin group of agents with an IC50 of < 5 μM for small cell lung carcinoma cell line H69. Artesunate is a semi-synthetic derivative of artemisinin that is water-soluble and may therefore be given by injection. Artesunate is used primarily as treatment for malaria; but artesunate has also been shown to be >90% efficacious at reducing egg production in Schistosoma haematobium infection.
Synonyms

Artesunic Acid; NSC 712571; WR 256283
Pathway

JAK/STAT Signaling
Target

STAT
Recptor

STAT
Research Area

Infection
Indication

——

CAS Number

88495-63-0
Formula Weight

384.42
Molecular Formula

C19H28O8
Purity

>98%(HPLC)
Solubility

Ethanol: 77 mg/mL (200.3 mM); DMSO: 77 mg/mL (200.3 mM)
SMILES

C[C@@H]1CC[C@H]2[C@@H](C)[C@H](OC(CCC(O)=O)=O)O[C@H]3[C@@]24[C@H]1CC[C@](OO4)(C)O3
Chemical Name

4-oxo-4-(((3R,5aS,6R,8aS,9R,10S,12R,12aR)-3,6,9-trimethyldecahydro-12H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl)oxy)butanoic acid

1.Cui C, et al. Int Immunopharmacol. 2015 Jul;27(1):110-2

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