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Artefenomel
CAS No. 1029939-86-3
Artefenomel ( OZ439 )
Catalog No. M10144 CAS No. 1029939-86-3
Artefenomel (OZ439) is a novel, next-generation antimalarial ozonide that demonstrates high potentcy against P. falciparum in vitro and P. berghei in vivo (K1/NF54, IC50=2.0/3.2 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 401 | Get Quote |
|
| 50MG | 1674 | Get Quote |
|
| 100MG | 2502 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameArtefenomel
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NoteResearch use only, not for human use.
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Brief DescriptionArtefenomel (OZ439) is a novel, next-generation antimalarial ozonide that demonstrates high potentcy against P. falciparum in vitro and P. berghei in vivo (K1/NF54, IC50=2.0/3.2 nM).
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DescriptionArtefenomel (OZ439) is a novel, next-generation antimalarial ozonide that demonstrates high potentcy against P. falciparum in vitro and P. berghei in vivo (K1/NF54, IC50=2.0/3.2 nM).Parasite Infection Phase 2 Clinical
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SynonymsOZ439
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PathwayMicrobiology/Virology
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TargetParasite
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RecptorParasite
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Research AreaInfection
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IndicationParasite Infection
Chemical Information
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CAS Number1029939-86-3
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Formula Weight469.62
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Molecular FormulaC28H39NO5
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Purity>98% (HPLC)
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Solubility——
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SMILESC1CC2(CCC1C3=CC=C(C=C3)OCCN4CCOCC4)OC5(C6CC7CC(C6)CC5C7)OO2
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Chemical Name4-[2-(4-cis-Dispiro[cyclohexane-1,3'-[1,2,4]trioxolane-5',2''-tricyclo[3.3.1.13,7]decan]-4-ylphenoxy)ethyl]morpholine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Dong Y, et al. J Med Chem. 2017 Apr 13;60(7):2654-2668.
2. Kim HS, et al. J Med Chem. 2017 Apr 13;60(7):2651-2653.
3. Macintyre F, et al. BMC Med. 2017 Oct 9;15(1):181.
4. Yang T, et al. Antimicrob Agents Chemother. 2016 Jul 22;60(8):4501-10.
2. Kim HS, et al. J Med Chem. 2017 Apr 13;60(7):2651-2653.
3. Macintyre F, et al. BMC Med. 2017 Oct 9;15(1):181.
4. Yang T, et al. Antimicrob Agents Chemother. 2016 Jul 22;60(8):4501-10.
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