Argireline
CAS No. 616204-22-9
Argireline ( Acetyl hexapeptide-3 )
Catalog No. M22308 CAS No. 616204-22-9
Argireline (Acetyl hexapeptide-3) is composed of chains of amino acids known as peptides. Argireline significantly inhibits Ca2+ dependent neurotransmitter release (acetylcholine) at the neuromuscular junction.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 43 | In Stock |
|
10MG | 52 | In Stock |
|
50MG | 60 | In Stock |
|
100MG | 97 | In Stock |
|
200MG | Get Quote | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
-
Product NameArgireline
-
NoteResearch use only, not for human use.
-
Brief DescriptionArgireline (Acetyl hexapeptide-3) is composed of chains of amino acids known as peptides. Argireline significantly inhibits Ca2+ dependent neurotransmitter release (acetylcholine) at the neuromuscular junction.
-
DescriptionArgireline (Acetyl hexapeptide-3) is composed of chains of amino acids known as peptides. Argireline significantly inhibits Ca2+ dependent neurotransmitter release (acetylcholine) at the neuromuscular junction. Argireline has antiwrinkle and anti-aging activity.The incubation of Argireline solution in different concentrations with human embryonic kidney HEK-293 (IC50 of 34.862 μM) and neuroblastoma IMR-32 cells (IC50 of 68.458 μM)) for 48 h have dose dependent antiproliferative effect. Argireline solution incubated in different concentrations with HSF has a dose-dependent antiproliferative effect on those cells. Cellular proliferation is not effected in Argireline low concentration.Argireline is applied to the aged mice twice daily for 6 weeks. There is an improvement in the histological structure of skin tissue in the aged mice; the amount of type I collagen fibers increased, while that of type III collagen fibers decreased. Argireline could improve the histological structure of skin tissue and rejuvenate the aging skin.
-
SynonymsAcetyl hexapeptide-3
-
PathwayOthers
-
TargetOther Targets
-
RecptorOthers
-
Research AreaOthers
-
IndicationWrinkles
Chemical Information
-
CAS Number616204-22-9
-
Formula Weight888.99
-
Molecular FormulaC34H60N14O12S
-
Purity>98% (HPLC)
-
SolubilityH2O:8.8 mg/mL (9.90 mM; Need ultrasonic and warming)
-
SMILESCC(=O)N[C@@H](CCC(=O)O)C(=C)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Blanes-Mira C, et al. A synthetic hexapeptide (Argireline) with antiwrinkle activity. Int J Cosmet Sci. 2002 Oct;24(5):303-10.
molnova catalog
related products
-
Platyconic acid A
Platyconic Acid A, derived from changkil saponins extracted from platycodon grandiflorum, is a potent compound employed for studying the mitigation of airway inflammation.
-
Palmitic acid ethyl ...
Used as softener and lubricant.
-
Lophanthoidin F
Lophanthoidin F is a kind of natural product derived from the herbs of Rabdosia lophanthoides.