
Apararenone
CAS No. 945966-46-1
Apararenone( MT-3995 | MT3995 )
Catalog No. M16779 CAS No. 945966-46-1
Apararenone (MT-3995) is a novel potent, selective non-steroidal mineralocorticoid receptor antagonist for the treatment of diabetic nephropathies and non-alcoholic steatohepatitis.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
5MG | 56 | Get Quote |
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10MG | 76 | Get Quote |
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25MG | 118 | Get Quote |
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50MG | 170 | Get Quote |
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100MG | 248 | Get Quote |
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200MG | Get Quote | Get Quote |
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500MG | Get Quote | Get Quote |
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1G | Get Quote | Get Quote |
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Biological Information
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Product NameApararenone
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NoteResearch use only, not for human use.
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Brief DescriptionApararenone (MT-3995) is a novel potent, selective non-steroidal mineralocorticoid receptor antagonist for the treatment of diabetic nephropathies and non-alcoholic steatohepatitis.
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DescriptionApararenone (MT-3995) is a novel potent, selective non-steroidal mineralocorticoid receptor antagonist for the treatment of diabetic nephropathies and non-alcoholic steatohepatitis.Steatohepatitis Phase 2 Clinical.
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In Vitro——
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In VivoRecently, a phase II clinical trial has been initiated among patients with non-alcoholic steatohepatitis (NASH) in Japan.
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SynonymsMT-3995 | MT3995
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PathwayNuclear Receptor/Transcription Factor
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TargetMLR
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RecptorMLR
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Research AreaOther Indications
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IndicationSteatohepatitis
Chemical Information
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CAS Number945966-46-1
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Formula Weight364.391
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Molecular FormulaC17H17FN2O4S
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 125 mg/mL 343.04 mM
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SMILESCS(=O)(NC1=CC=C2N(C3=CC=C(F)C=C3)C(C(C)(C)OC2=C1)=O)=O
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Chemical NameN-(4-(4-fluorophenyl)-2,2-dimethyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-7-yl)methanesulfonamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Kolkhof P, et al. Curr Opin Nephrol Hypertens. 2015 Sep;24(5):417-24.
2. Kolkhof P, et al. J Endocrinol. 2017 Jul;234(1):T125-T140.
molnova catalog



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