Cart
sales@molnova.com
Apafant
CAS No. 105219-56-5
Apafant( —— )
Catalog No. M33267 CAS No. 105219-56-5
Apafant (WEB 2086) is a highly potent platelet activating factor (PAF) antagonist that blocks eosinophil activation and can be used to study experimental allergic conjunctivitis in guinea pigs.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 172 | In Stock |
|
| 5MG | 275 | In Stock |
|
| 10MG | 407 | In Stock |
|
| 25MG | 642 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameApafant
-
NoteResearch use only, not for human use.
-
Brief DescriptionApafant (WEB 2086) is a highly potent platelet activating factor (PAF) antagonist that blocks eosinophil activation and can be used to study experimental allergic conjunctivitis in guinea pigs.
-
DescriptionApafant (WEB 2086), a potent platelet-activating factor (PAF) antagonist, inhibits PAF binding to human PAF receptors with a Ki of 9.9 nM.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorPAFR
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number105219-56-5
-
Formula Weight455.96
-
Molecular FormulaC22H22ClN5O2S
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 40 mg/mL (87.73 mM )
-
SMILESO=C(N1CCOCC1)CCC=2SC3=C(C2)C(=NCC4=NN=C(N43)C)C=5C=CC=CC5Cl
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Kato M, et al. Apafant, a potent platelet-activating factor antagonist, blocks eosinophil activation and is effective in the chronic phase of experimental allergic conjunctivitis in guinea pigs. J Pharmacol Sci. 2004 Aug;95(4):435-42.?
molnova catalog
related products
-
Herbacetin 3-sophoro...
The herbs of Rhodiola rosea.
-
Ethyl oleate
Ethyl oleate is the liquid lipid component in nanostructured lipid carriers (NLCs).?NLC is a promising vehicle for oral trans-Ferulic acid (TFA) administration.?
-
Hepcidin-1 (mouse) t...
Hepcidin-1 (mouse) is an endogenous peptide hormone involved in the regulation of iron homeostasis. Hepcidin-1 (mouse) upregulates mRNA levels of TRAP, cathepsin K, and MMP-9 and increases TRAP-5b protein secretion. Hepcidin-1 (mouse) downregulates the level of FPN1 protein and increases intracellular iron. Hepcidin-1 (mouse) facilitates osteoclast differentiation.
