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Apafant
CAS No. 105219-56-5
Apafant( —— )
Catalog No. M33267 CAS No. 105219-56-5
Apafant (WEB 2086) is a highly potent platelet activating factor (PAF) antagonist that blocks eosinophil activation and can be used to study experimental allergic conjunctivitis in guinea pigs.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 172 | In Stock |
|
| 5MG | 275 | In Stock |
|
| 10MG | 407 | In Stock |
|
| 25MG | 642 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameApafant
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NoteResearch use only, not for human use.
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Brief DescriptionApafant (WEB 2086) is a highly potent platelet activating factor (PAF) antagonist that blocks eosinophil activation and can be used to study experimental allergic conjunctivitis in guinea pigs.
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DescriptionApafant (WEB 2086), a potent platelet-activating factor (PAF) antagonist, inhibits PAF binding to human PAF receptors with a Ki of 9.9 nM.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorPAFR
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Research Area——
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Indication——
Chemical Information
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CAS Number105219-56-5
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Formula Weight455.96
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Molecular FormulaC22H22ClN5O2S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 40 mg/mL (87.73 mM )
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SMILESO=C(N1CCOCC1)CCC=2SC3=C(C2)C(=NCC4=NN=C(N43)C)C=5C=CC=CC5Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Kato M, et al. Apafant, a potent platelet-activating factor antagonist, blocks eosinophil activation and is effective in the chronic phase of experimental allergic conjunctivitis in guinea pigs. J Pharmacol Sci. 2004 Aug;95(4):435-42.?
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