Aniline

Research use only not for human use.

Aniline has been reported to be toxic to the spleen via iron overload and induction of oxidative stress via Heme Oxygenase 1 up-regulation.

Aniline has been reported to be toxic to the spleen via iron overload and induction of oxidative stress via Heme Oxygenase 1 up-regulation. Toxicity of this agent on the spleen is characterized by hyperplasia fibrosis and vascular congestion in rats. Studies suggest that this compound causes significant increase in both p-IKKα and p-IKKβ which in-turn increases NF-κB and AP-1 binding activity. In other experiments Aniline displays a capacity to induce methemoglobinemia glutathione depletion membrane cytoskeletal changes loss of circulating blood cells and adversely affects blood stability.

Phenylamine;Aminobenzen

Proteasome/Ubiquitin

Endogenous Metabolite

Human Endogenous Metabolite

——

——

62-53-3

93.13

C6H7N

>98% (HPLC)

DMSO:10 mM

Nc1ccccc1

——

(-20℃)

With Ice Pack

≥ 2 years