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Anemonin

CAS No. 90921-11-2

Anemonin( —— )

Catalog No. M29028 CAS No. 90921-11-2

Anemonin is a natural product from Pulsatilla chinensis Regel.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Anemonin
  • Note
    Research use only, not for human use.
  • Brief Description
    Anemonin is a natural product from Pulsatilla chinensis Regel.
  • Description
    Anemonin is a natural product from Pulsatilla chinensis Regel.(In Vitro):Human articular chondrocytes and cartilage explants challenged with interleukin-1β (IL-1β) were treated with Anemonin. Anemonin treatment attenuated proteoglycan loss in human cartilage explants treated with IL-1β ex vivo. Anemonin delayed articular cartilage degeneration in vitro. (In Vivo):Destabilization of the medial meniscus (DMM) was performed in 10-week-old male C57BL/6J mice. Anemonin was then intra-articularly injected into the joint capsule for 8 and 12 weeks. Anemonin delayed articular cartilage degeneration in vivo. Anemonin decreased the expressions of matrix metalloproteinase-13 (MMP13), A disintegrin, and metalloproteinase with thrombospondin motifs 5 (ADAMTS5), collagen X (Col X) while increasing Aggrecan level in murine with DMM surgery. Proteoglycan loss and chondrocyte hypertrophy were significantly decreased in Anemonin-treated mice compared with vehicle-treated mice.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    90921-11-2
  • Formula Weight
    192.17
  • Molecular Formula
    C10H8O4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C1OC2(CCC22OC(=O)C=C2)C=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

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