Analgin

CAS No. 5907-38-0

Analgin( Dipyrone | NSC-73205 | NSC 73205 | NSC73205 | Anador | Novalgin )

Catalog No. M15189 CAS No. 5907-38-0

A drug that has analgesic, anti-inflammatory, and antipyretic properties.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
200MG 89 In Stock
500MG Get Quote In Stock
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Biological Information

  • Product Name
    Analgin
  • Note
    Research use only, not for human use.
  • Brief Description
    A drug that has analgesic, anti-inflammatory, and antipyretic properties.
  • Description
    A drug that has analgesic, anti-inflammatory, and antipyretic properties. It is the sodium sulfonate of aminopyrine. Because of the risk of serious adverse effects its use is justified only in serious situations where no alternative is available or suitable.
  • In Vitro
    Cell Proliferation Assay Cell Line:PaTu 8988 t, Panc-1 Concentration:1, 10, 100, 250, 500 μM Incubation Time:48 h Result:Inhibited proliferation in the PaTu 8988 t cell line with 1–500 μM and with concentrations of 1 μM, 10 μM, 100 μM, and 250 μM in the Panc-1 cell line.
  • In Vivo
    Animal Model:Neuropathic pain rat model Dosage:500 mg/kg Administration:intraperitoneally preemptively at 16 and 1 h before Chronic constriction injury (CCI) and then twice a day for 7 days.Result:Decreased the expression of pronociceptive interleukins (IL-1beta, IL-6, and IL-18) and chemokines (CCL2, CCL4, and CCL7).Animal Model:Pain model in rats Dosage:250 or 500 mg/kg Administration:p.o.Result:Decreased the COX-2 gene expression at 500 mg/kg and increased the MPO gene expression.Reduced MDA levels in the carrageenan paw test and increased tGSH levels.
  • Synonyms
    Dipyrone | NSC-73205 | NSC 73205 | NSC73205 | Anador | Novalgin
  • Pathway
    Chromatin/Epigenetic
  • Target
    COX
  • Recptor
    COX-1
  • Research Area
    Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    5907-38-0
  • Formula Weight
    333.34
  • Molecular Formula
    C13H16N3NaO4S
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    O=S(CN(C1=C(C)N(C)N(C2=CC=CC=C2)C1=O)C)([O-])=O.[H]O[H].[Na+]
  • Chemical Name
    sodium ((1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)(methyl)amino)methanesulfonate hydrate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
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