Ampalex
CAS No. 154235-83-3
Ampalex( Ampalex | BDP-12 | Benzoyl-Piperidine-12 )
Catalog No. M12187 CAS No. 154235-83-3
Ampalex (Ampakine CX516; CX516; BDP 12) is an ampakine and nootropic that acts as an AMPA receptor positive allosteric modulator as a treatment for Alzheimer's disease.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 29 | In Stock |
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| 10MG | 47 | In Stock |
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| 25MG | 57 | In Stock |
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| 50MG | 88 | In Stock |
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| 100MG | 113 | In Stock |
|
| 200MG | 203 | In Stock |
|
| 500MG | 339 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAmpalex
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NoteResearch use only, not for human use.
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Brief DescriptionAmpalex (Ampakine CX516; CX516; BDP 12) is an ampakine and nootropic that acts as an AMPA receptor positive allosteric modulator as a treatment for Alzheimer's disease.
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DescriptionAmpalex (Ampakine CX516; CX516; BDP 12) is an ampakine and nootropic that acts as an AMPA receptor positive allosteric modulator as a treatment for Alzheimer's disease, schizophrenia and mild cognitive impairment (MCI).(In Vitro):.(In Vivo):The specific extradimensional deficits produced by sub-chronic or early postnatal postnatal phencyclidine treatment were significantly attenuated by CX516 (10, and 20 mg/kg, s.c.).
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In Vitro——
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In VivoThe specific extradimensional deficits produced by sub-chronic or early postnatal postnatal phencyclidine treatment were significantly attenuated by CX516 (10, and 20 mg/kg, s.c.). Animal Model:Male Lister Hooded rats (56-63 postnatal day)Dosage:5, 10, 20, and 40 mg/kg Administration:Subcutaneously Result:Two doses (10 and 20 mg/kg) were highly significant in improving the extradimensional shift deficit induced by either treatment regimes. Two doses (5 and 40 mg/kg) was ineffective at reversing the extradimensional impairment induced by the sub-chronic postnatal phencyclidine treatment regime.
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SynonymsAmpalex | BDP-12 | Benzoyl-Piperidine-12
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PathwayNeuroscience
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TargetGluR
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RecptorAMPA
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number154235-83-3
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Formula Weight241.29
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Molecular FormulaC14H15N3O
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Purity>98% (HPLC)
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SolubilityDMSO: 40 mg/mL
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SMILESO=C(N1CCCCC1)C2=CC=C3N=CC=NC3=C2
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Chemical Name1-(quinoxalin-6-ylcarbonyl)piperidine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Broberg BV, et al. Psychopharmacology (Berl). 2009 Nov;206(4):631-40.
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