Amlexanox

CAS No. 68302-57-8

Amlexanox( AA 673 | CHX 3673 | Elics )

Catalog No. M15611 CAS No. 68302-57-8

Amlexanox (AA673; CHX3673) is a specific inhibitor of IKKε and TBK1; inhibition of IKKε and TBK1 activity as determined by MBP phosphorylation showing an IC50 of approximately 1–2 μM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 29 In Stock
10MG 45 In Stock
25MG 50 In Stock
50MG 71 In Stock
100MG 87 In Stock
200MG Get Quote In Stock
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Biological Information

  • Product Name
    Amlexanox
  • Note
    Research use only, not for human use.
  • Brief Description
    Amlexanox (AA673; CHX3673) is a specific inhibitor of IKKε and TBK1; inhibition of IKKε and TBK1 activity as determined by MBP phosphorylation showing an IC50 of approximately 1–2 μM.
  • Description
    Amlexanox (AA673; CHX3673) is a specific inhibitor of IKKε and TBK1; inhibition of IKKε and TBK1 activity as determined by MBP phosphorylation showing an IC50 of approximately 1–2 μM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    AA 673 | CHX 3673 | Elics
  • Pathway
    Angiogenesis
  • Target
    FGFR
  • Recptor
    FGFR1| IL-3| Protein S100-P
  • Research Area
    Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    68302-57-8
  • Formula Weight
    298.29
  • Molecular Formula
    C16H14N2O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 100 mM
  • SMILES
    CC(C)C1=CC2=C(C=C1)OC3=NC(=C(C=C3C2=O)C(=O)O)N
  • Chemical Name
    2-amino-5-oxo-7-propan-2-ylchromeno[2,3-b]pyridine-3-carboxylic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Shishibori T, et al. Biochem J. 1999 Mar 15;338 ( Pt 3):583-9.
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