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Amino-PEG13-amine

CAS No. 1228119-65-0

Amino-PEG13-amine( H2N-PEG13-CH2CH2NH2 )

Catalog No. M26885 CAS No. 1228119-65-0

Amino-PEG13-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Amino-PEG13-amine
  • Note
    Research use only, not for human use.
  • Brief Description
    Amino-PEG13-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
  • Description
    Amino-PEG13-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vitro
    PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vivo
    ——
  • Synonyms
    H2N-PEG13-CH2CH2NH2
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    CK2| Clk2/CK2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1228119-65-0
  • Formula Weight
    632.789
  • Molecular Formula
    C28H60N2O13
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (158.03 mM)
  • SMILES
    NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Wang Y, et, al. Discovery of 5-(3-Chlorophenylamino)benzo[ c][2,6]naphthyridine Derivatives as Highly Selective CK2 Inhibitors with Potent Cancer Cell Stemness Inhibition. J Med Chem. 2021 Apr 22;64(8):5082-5098.
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