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Amino-PEG12-amine

CAS No. 361543-12-6

Amino-PEG12-amine( H2N-PEG12-CH2CH2NH2 | PEODA13 )

Catalog No. M26883 CAS No. 361543-12-6

Amino-PEG12-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Amino-PEG12-amine
  • Note
    Research use only, not for human use.
  • Brief Description
    Amino-PEG12-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
  • Description
    Amino-PEG12-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vitro
    PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vivo
    ——
  • Synonyms
    H2N-PEG12-CH2CH2NH2 | PEODA13
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Antimalarial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    361543-12-6
  • Formula Weight
    588.736
  • Molecular Formula
    C26H56N2O12
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Taft BR, et, al. Discovery and Preclinical Pharmacology of INE963, a Potent and Fast-Acting Blood-Stage Antimalarial with a High Barrier to Resistance and Potential for Single-Dose Cures in Uncomplicated Malaria. J Med Chem. 2022 Mar 10;65(5):3798-3813.
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