Amino-PEG12-alcohol ( —— )

Catalog No. M26882 CAS No. 1345681-71-1

Amino-PEG12-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

Amino-PEG12-alcohol
Note

Research use only, not for human use.
Brief Description

Amino-PEG12-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Description

Amino-PEG12-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

TLR7; TLR8
Research Area

——
Indication

——

Chemical Information

CAS Number

1345681-71-1
Formula Weight

545.7
Molecular Formula

C24H51NO12
Purity

>98% (HPLC)
Solubility

——
SMILES

NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Jaromir Vlach, et al. Discovery of M5049: A Novel Selective TLR7/8 Inhibitor for Treatment of Autoimmunity. J Pharmacol Exp Ther. 2020 Dec 16;JPET-AR-2020-000275.

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