Alosetron ( GR-68755X;GR-68755 )

Catalog No. M10888 CAS No. 122852-42-0

A potent and selective 5-HT3 receptor antagonist has been shown to be beneficial in the treatment of irritable bowel syndrome.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

Alosetron
Note

Research use only, not for human use.
Brief Description

A potent and selective 5-HT3 receptor antagonist has been shown to be beneficial in the treatment of irritable bowel syndrome.
Description

A potent and selective 5-HT3 receptor antagonist has been shown to be beneficial in the treatment of irritable bowel syndrome.Irritable Bowel Syndrome Approved
Synonyms

GR-68755X;GR-68755
Pathway

Endocrinology/Hormones
Target

5-HT Receptor
Recptor

5-HT Receptor
Research Area

Other Indications
Indication

Irritable Bowel Syndrome

Chemical Information

CAS Number

122852-42-0
Formula Weight

294.35
Molecular Formula

C17H18N4O
Purity

>98% (HPLC)
Solubility

10 mM in DMSO
SMILES

Cc1c([nH]cn1)CN2CCc3c(c4ccccc4n3C)C2=O
Chemical Name

1H-Pyrido[4,3-b]indol-1-one, 2,3,4,5-tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Audolfsson G, et al. Aliment Pharmacol Ther. 1999 May;13 Suppl 2:39-47.
2. Zhai J, et al. J Pharmacol Exp Ther. 1999 Oct;291(1):374-82.
3. Saslow SB, et al. Gut. 1998 May;42(5):628-34.

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