Afimetoran

CAS No. 2171019-55-7

Afimetoran( BMS-986256 )

Catalog No. M28229 CAS No. 2171019-55-7

Afimetoran is a toll-like receptor antagonist, which can be used in the research of inflammatory and autoimmune diseases.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 177 Get Quote
10MG 295 Get Quote
25MG 502 Get Quote
50MG 709 Get Quote
100MG 1008 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Afimetoran
  • Note
    Research use only, not for human use.
  • Brief Description
    Afimetoran is a toll-like receptor antagonist, which can be used in the research of inflammatory and autoimmune diseases.
  • Description
    Afimetoran is a toll-like receptor antagonist, which can be used in the research of inflammatory and autoimmune diseases.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    BMS-986256
  • Pathway
    Immunology/Inflammation
  • Target
    TLR
  • Recptor
    mitotic kinesin Kif18A
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2171019-55-7
  • Formula Weight
    444.57
  • Molecular Formula
    C26H32N6O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (224.94 mM)
  • SMILES
    CC(C)c1c(-c2cn3ncnc3c(C)c2C)[nH]c2c1cc(C1CCN(CC(N)=O)CC1)cc2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Tamayo NA, et al. Targeting the Mitotic Kinesin KIF18A in Chromosomally Unstable Cancers: Hit Optimization Toward an In Vivo Chemical Probe. J Med Chem. 2022;65(6):4972-4990.
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