Adrenochrome

CAS No. 54-06-8

Adrenochrome( —— )

Catalog No. M33656 CAS No. 54-06-8

Adrenochrome (Adraxone) is a cytotoxic molecule that can be used to kill bacteria. Adrenochrome is an oxidized product of Epinephrine.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Adrenochrome
  • Note
    Research use only, not for human use.
  • Brief Description
    Adrenochrome (Adraxone) is a cytotoxic molecule that can be used to kill bacteria. Adrenochrome is an oxidized product of Epinephrine.
  • Description
    Adrenochrome (Adraxone) is an oxidation product of Epinephrine. Adrenochrome is a potent coronary constricting agent in the rat heart. Adrenochrome can be used for neurological disorder research.
  • In Vitro
    Adrenochrome decreases microsomal calcium binding, calcium uptake and Ca2+-stimulated Mg2+-dependent ATPase activities. The inhibitory effect of Adrenochrome on microsomal calcium uptake activity of the isolated membrane is independent of pH (6.0-8.0), calcium concentrations (10-200 μM), protein concentration (0.02-0.10 mg/mL), temperature (25-37 degrees C) and incubation time (2-30 min).
  • In Vivo
    In isolated rat hearts, concentrations of Adrenochrome from 1 to 1000 ng/mL increases coronary pressure in a dose- and time-dependent manner. Furthermore, the degree of constriction by Adrenochrome is dependent on the CaCl2 concentration in the perfusion medium.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Antioxidant
  • Recptor
    Antioxidant
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    54-06-8
  • Formula Weight
    179.17
  • Molecular Formula
    C9H9NO3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (558.13 mM; Ultrasonic )
  • SMILES
    OC1C=2C(N(C)C1)=CC(=O)C(=O)C2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. M Karmazyn,, et al. Adrenochrome-induced coronary artery constriction in the rat heart. J Pharmacol Exp Ther. 1981 Oct;219(1):225-30.?
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