Adjudin
CAS No. 252025-52-8
Adjudin ( AF-2364; AF 2364; AF2364; Adjudin )
Catalog No. M17455 CAS No. 252025-52-8
Adjudin is a small molecule compound known to possess antispermatogenic function, attenuates microglia activation by suppression of the NF-κB pathway.
Purity : 97%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 43 | In Stock |
|
10MG | 68 | In Stock |
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25MG | 105 | In Stock |
|
50MG | 141 | In Stock |
|
100MG | 214 | In Stock |
|
500MG | 536 | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
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Product NameAdjudin
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NoteResearch use only, not for human use.
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Brief DescriptionAdjudin is a small molecule compound known to possess antispermatogenic function, attenuates microglia activation by suppression of the NF-κB pathway.
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DescriptionAdjudin, also known as AF-2364, is a drug which is under development as a potential non-hormonal male contraceptive drug, which acts by blocking the production of sperm in the testes, but without affecting testosterone production. It is an analogue of the chemotherapy drug lonidamine, an indazole-carboxylic acid, and further studies continue to be conducted into this family of drugs as possible contraceptives. A study in 2013 indicated that Adjudin, similar to its analogue lonidamine, has properties that inhibit cancer growth by targeting mitochondria and blocking energy metabolism in certain kinds of tumor cells in mice, indicating that it has potential as a drug for cancer therapy.
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SynonymsAF-2364; AF 2364; AF2364; Adjudin
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research AreaOthers-Field
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Indication——
Chemical Information
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CAS Number252025-52-8
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Formula Weight335.19
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Molecular FormulaC15H12Cl2N4O
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Purity97%
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SolubilityDMSO : ≥ 34 mg/mL; 101.44 mM
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SMILESClc1c(Cn2nc(c3c2cccc3)C(=O)NN)ccc(Cl)c1
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Chemical Name1-(2,4-dichlorobenzyl)-1H-indazole-3-carbohydrazide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Mruk DD. Trends Endocrinol Metab. 2008 Mar;19(2):57-64.
molnova catalog
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