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Home - Products - JAK/STAT Signaling - STAT - Acetyl-trans-resveratrol

Acetyl-trans-resveratrol

CAS No. 42206-94-0

Acetyl-trans-resveratrol( —— )

Catalog No. M20344 CAS No. 42206-94-0

Acetyl-trans-resveratrol has anti-cancer activityit inhibits the phosphorylation of STAT3 and NFκB down-regulates Mcl-1 and up-regulates Bim and Puma in pancreatic cancer cells.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    Acetyl-trans-resveratrol
  • Note
    Research use only, not for human use.
  • Brief Description
    Acetyl-trans-resveratrol has anti-cancer activityit inhibits the phosphorylation of STAT3 and NFκB down-regulates Mcl-1 and up-regulates Bim and Puma in pancreatic cancer cells.
  • Description
    Acetyl-trans-resveratrol has anti-cancer activityit inhibits the phosphorylation of STAT3 and NFκB down-regulates Mcl-1 and up-regulates Bim and Puma in pancreatic cancer cells.
  • In Vitro
    Triacetylresveratrol significantly down-regulates anti-apoptotic Bcl-2 family protein Mcl-1 and up-regulates pro-apoptotic Bcl-2 family proteins Bim and Puma. Triacetylresveratrol inhibits cell viability, and induces apoptosis of pancreatic cancer cells in a concentration and incubation time-dependent manner.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    JAK/STAT Signaling
  • Target
    STAT
  • Recptor
    STAT3|Mcl-1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    42206-94-0
  • Formula Weight
    354.35
  • Molecular Formula
    C20H18O6
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:50mg/m(141.24 mM)
  • SMILES
    CC(=O)Oc1ccc(cc1)\C=C\c1cc(OC(C)=O)cc(OC(C)=O)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Duan J J Yue W Jianyu E et al. In vitro comparative studies of resveratrol and triacetylresveratrol on cell proliferation apoptosis and STAT3 and NFκB signaling in pancreatic cancer cells[J]. Scientific Reports 2016 6:31672.
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