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Ac-Pro-Gly-Pro-OH

CAS No. 292171-04-1

Ac-Pro-Gly-Pro-OH( —— )

Catalog No. M36655 CAS No. 292171-04-1

Ac-Pro-Gly-Pro-OH is an acetyl-modified tripeptide compound that acts as a CXCR2 agonist, exhibiting bactericidal and anti-inflammatory activities.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Ac-Pro-Gly-Pro-OH
  • Note
    Research use only, not for human use.
  • Brief Description
    Ac-Pro-Gly-Pro-OH is an acetyl-modified tripeptide compound that acts as a CXCR2 agonist, exhibiting bactericidal and anti-inflammatory activities.
  • Description
    Ac-Pro-Gly-Pro-OH is an endogenous degradation product of extracellular collagen and can be used as CXCR2 agonist. Ac-Pro-Gly-Pro-OH elicits bactericidal activity and inhibits lung inflammation, reducing immune cell apoptosis. Ac-Pro-Gly-Pro-OH enhances the production of type 1 cytokines (IFN-γ and IL-12) but inhibits the production of proinflammatory cytokines. Ac-Pro-Gly-Pro-OH has the potential for the research of sepsis.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    Apoptosis
  • Recptor
    Apoptosis | CXCR | Antibiotic
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    292171-04-1
  • Formula Weight
    311.33
  • Molecular Formula
    C14H21N3O5
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(NCC(=O)N1[C@H](C(O)=O)CCC1)(=O)[C@H]2N(C(C)=O)CCC2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Patel DF, et al The multifaceted roles of the matrikine Pro-Gly-Pro in pulmonary health and disease. Eur Respir Rev. 2018 Jun 27;27(148):180017.?
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