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Ac-DEVD-AMC

CAS No. 169332-61-0

Ac-DEVD-AMC( AC-ASP-MET-GLN-ASP-7-AMINO-4-METHYLCOUMARIN | AC-ASP-MET-GLN-ASP-AMC )

Catalog No. M27032 CAS No. 169332-61-0

Ac-DEVD-AMC is the substrate of Caspase-3 .

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Ac-DEVD-AMC
  • Note
    Research use only, not for human use.
  • Brief Description
    Ac-DEVD-AMC is the substrate of Caspase-3 .
  • Description
    Ac-DEVD-AMC is the substrate of Caspase-3 .(In Vitro):The AMC moiety is highest at 2 h with an area of 5.6±1.8, the AMC peak area for Ac-DEVD-AMC incubated without a lung specimen (substrate alone) for 6 h is relatively small . Ac-DEVD-AMC can be used to monitor intracellular caspase-3 activity.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    AC-ASP-MET-GLN-ASP-7-AMINO-4-METHYLCOUMARIN | AC-ASP-MET-GLN-ASP-AMC
  • Pathway
    Apoptosis
  • Target
    Caspase
  • Recptor
    AMPA
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    169332-61-0
  • Formula Weight
    675.648
  • Molecular Formula
    C30H37N5O13
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : 0.67 mg/mL (0.99 mM)
  • SMILES
    CC(C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(C)=O)C(=O)N[C@@H](CC(O)=O)C(=O)Nc1ccc2c(C)cc(=O)oc2c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.BERRY CYNTHIA G B (US), et al. AZABENZIMIDAZOLES AND THEIR USE AS AMPA RECEPTOR MODULATORS. Patent. WO2016176460.
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