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AZD9898

CAS No. 2042347-69-1

AZD9898 ( —— )

Catalog No. M26621 CAS No. 2042347-69-1

AZD9898 is an orally active leukotriene-C4 synthetase (LTC4S, glutathione S-transferase II) inhibitor, with an IC50 of 0.28 nM. AZD9898 has the potential to treat asthma. AZD9898 mitigates the GABA binding and hepatic toxicity signal.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    AZD9898
  • Note
    Research use only, not for human use.
  • Brief Description
    AZD9898 is an orally active leukotriene-C4 synthetase (LTC4S, glutathione S-transferase II) inhibitor, with an IC50 of 0.28 nM. AZD9898 has the potential to treat asthma. AZD9898 mitigates the GABA binding and hepatic toxicity signal.
  • Description
    AZD9898 is an orally active leukotriene-C4 synthetase (LTC4S, glutathione S-transferase II) inhibitor, with an IC50 of 0.28 nM. AZD9898 has the potential to treat asthma. AZD9898 mitigates the GABA binding and hepatic toxicity signal.(In Vivo):AZD9898 (10 and 100 mg/kg; oral) is well tolerated and shows no safety concerns.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Antifungal
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2042347-69-1
  • Formula Weight
    457.8
  • Molecular Formula
    C20H19ClF3N3O4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    COc1nc(cnc1C(=O)[C@H]1C[C@@H]1C(O)=O)N(CC(C)(C)F)c1cc(Cl)c(F)cc1F
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.S Boukaew, et al. Efficacy of volatile compounds from Streptomyces philanthi RL-1-178 as a biofumigant for controlling growth and aflatoxin production of the two aflatoxin-producing fungi on stored soybean seeds. J Appl Microbiol. 2020 Sep;129(3):652-664.
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