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AZD0780

CAS No. 2455427-91-3

AZD0780( —— )

Catalog No. M35805 CAS No. 2455427-91-3

AZD0780 (EX-A6975) is an oral small molecule PCSK9 inhibitor being developed by AstraZeneca as a first-in-class treatment for patients with dyslipidemia that is uncontrolled with statins alone.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 141 Get Quote
5MG 217 Get Quote
10MG 353 Get Quote
25MG 579 Get Quote
50MG 824 Get Quote
100MG 1098 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
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Biological Information

  • Product Name
    AZD0780
  • Note
    Research use only, not for human use.
  • Brief Description
    AZD0780 (EX-A6975) is an oral small molecule PCSK9 inhibitor being developed by AstraZeneca as a first-in-class treatment for patients with dyslipidemia that is uncontrolled with statins alone.
  • Description
    PCSK9-IN-12 is a heteroaryl compound. PCSK9-IN-12has bind affinity for PCSK9with a Kd value of ＜200 nM. PCSK9-IN-12 can be used for the research of cholesterol metabolism.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2455427-91-3
  • Formula Weight
    414.41
  • Molecular Formula
    C20H20F2N6O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (241.31 mM; Ultrasonic )
  • SMILES
    FC(F)Oc1cnc(N[C@H]2CC[C@@H](C2)Nc2ccc(cn2)-n2ccccc2=O)nc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Michael H. Serrano-Wu, et al. Pcsk9 inhibitors and methods of use thereof. Patent. WO2020150474A1.
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