AZ13705339

CAS No. 2016806-57-6

AZ13705339 ( AZ-13705339; AZ 13705339 )

Catalog No. M27853 CAS No. 2016806-57-6

AZ13705339 is a potent and selective PAK1 inhibitor with IC50 of 0.33 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 35 Get Quote
5MG 58 Get Quote
10MG 88 Get Quote
25MG 200 Get Quote
50MG 320 Get Quote
100MG 515 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    AZ13705339
  • Note
    Research use only, not for human use.
  • Brief Description
    AZ13705339 is a potent and selective PAK1 inhibitor with IC50 of 0.33 nM.
  • Description
    AZ13705339 is a potent and selective PAK1 inhibitor with IC50 of 0.33 nM.(In Vitro):AZ13705339 (300 nM) prevents Siglec-8 binding-induced eosinophil death. In Namalwa cells, AZ13705339 (1 μM) inhibits αIgM-controlled but not PMA-induced adhesion.(In Vivo):In rats, AZ13705339 (100 mg/kg, p.o.) exhibits moderate clearance and Cmax of 7.7 μM.
  • Synonyms
    AZ-13705339; AZ 13705339
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2016806-57-6
  • Formula Weight
    629.8
  • Molecular Formula
    C33H36FN7O3S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CCS(=O)(=O)c1cc(Nc2ncc(F)c(n2)N(Cc2ccccc2C#N)c2cc(CO)ccc2C)ccc1N1CCN(C)CC1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Andrew F Ducruet , et al. GM1485, a Nonimmunosuppressive Immunophilin Ligand, Promotes Neurofunctional Improvement and Neural Regeneration Following Stroke. J Neurosci Res. 2012 Jul;90(7):1413-23.
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