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AZ044
CAS No. 1800017-49-5
AZ044( —— )
Catalog No. M34168 CAS No. 1800017-49-5
AZ044 is a potent, selective inhibitor of type III phosphatidylinositol-4-kinase alpha-subtype (PI4KIIIalpha).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 79 | Get Quote |
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| 5MG | 117 | Get Quote |
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| 10MG | 188 | Get Quote |
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| 25MG | 419 | Get Quote |
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| 50MG | 724 | Get Quote |
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| 100MG | 1152 | Get Quote |
|
| 200MG | 1557 | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameAZ044
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NoteResearch use only, not for human use.
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Brief DescriptionAZ044 is a potent, selective inhibitor of type III phosphatidylinositol-4-kinase alpha-subtype (PI4KIIIalpha).
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DescriptionPI4K-IN-1 (compound 44) is a potent PI4KIII inhibitor, with pIC50 values of 9.0 and 6.6 for PI4KIIIα and PI4KIIIβ, respectively. PI4K-IN-1 also inhibits PI3Kα/β/γ/δ, with pIC50 values of 4.0/<3.7/5.0/<4.1, respectively.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayPI3K/Akt/mTOR signaling
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TargetPI4K
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RecptorPI4K
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Research Area——
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Indication——
Chemical Information
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CAS Number1800017-49-5
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Formula Weight437.55
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Molecular FormulaC24H27N3O3S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (285.68 mM; Ultrasonic )
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SMILESN(C[C@@H]1CC[C@@H](C(O)=O)CC1)C=2SC=3C(N2)=CC=C(C3)C4=CC(=O)N(CC5CC5)C=C4
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Raubo P, et al. Discovery of potent, selective small molecule inhibitors of α-subtype of type III phosphatidylinositol-4-kinase (PI4KIIIα). Bioorg Med Chem Lett. 2015 Aug 15;25(16):3189-93. ?
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