AZ-Dyrk1B-33 ( 3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine )

Catalog No. M26618 CAS No. 1679330-37-0

AZ-Dyrk1B-33 is a potent and selective Dyrk1B kinase inhibitor with an IC50 of 7 nM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

AZ-Dyrk1B-33
Note

Research use only, not for human use.
Brief Description

AZ-Dyrk1B-33 is a potent and selective Dyrk1B kinase inhibitor with an IC50 of 7 nM.
Description

AZ-Dyrk1B-33 is a potent and selective Dyrk1B kinase inhibitor with an IC50 of 7 nM.(In Vitro):Administration of AZ-Dyrk1B-33 shows inhibition of phosphorylation of Dyrk pS421 in cells with an IC50 of 0.192 μM and no effect in sensitization.
Synonyms

3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine
Pathway

Others
Target

Other Targets
Recptor

CYP73A
Research Area

——
Indication

——

Chemical Information

CAS Number

1679330-37-0
Formula Weight

300.4
Molecular Formula

C19H16N4
Purity

>98% (HPLC)
Solubility

——
SMILES

Cc1nccc(n1)-c1cn(Cc2ccccc2)c2cnccc12
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.1. Schalk M, et al, Werck-Reichhart D. Piperonylic acid, a selective, mechanism-based inactivator of the trans-cinnamate 4-hydroxylase: A new tool to control the flux of metabolites in the phenylpropanoid pathway. Plant Physiol. 1998;118(1):209‐218.

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