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AZ-Dyrk1B-33
CAS No. 1679330-37-0
AZ-Dyrk1B-33( 3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine )
Catalog No. M26618 CAS No. 1679330-37-0
AZ-Dyrk1B-33 is a potent and selective Dyrk1B kinase inhibitor with an IC50 of 7 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 147 | Get Quote |
|
| 10MG | 237 | Get Quote |
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| 25MG | 480 | Get Quote |
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| 50MG | 698 | Get Quote |
|
| 100MG | 972 | Get Quote |
|
| 500MG | 1953 | Get Quote |
|
| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameAZ-Dyrk1B-33
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NoteResearch use only, not for human use.
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Brief DescriptionAZ-Dyrk1B-33 is a potent and selective Dyrk1B kinase inhibitor with an IC50 of 7 nM.
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DescriptionAZ-Dyrk1B-33 is a potent and selective Dyrk1B kinase inhibitor with an IC50 of 7 nM.(In Vitro):Administration of AZ-Dyrk1B-33 shows inhibition of phosphorylation of Dyrk pS421 in cells with an IC50 of 0.192 μM and no effect in sensitization.
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In VitroAZ-Dyrk1B-33 shows inhibition of phosphorylation of Dyrk pS421 in cells with an IC50 of 0.192 μM.AZ-Dyrk1B-33 shows no effect in sensitization.
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In Vivo——
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Synonyms3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine
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PathwayOthers
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TargetOther Targets
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RecptorCYP73A
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Research Area——
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Indication——
Chemical Information
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CAS Number1679330-37-0
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Formula Weight300.365
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Molecular FormulaC19H16N4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (416.17 mM)
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SMILESCc1nccc(n1)-c1cn(Cc2ccccc2)c2cnccc12
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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CPS-11
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IMR-1A
IMR-1A is the metabolite of IMR-1 which is a novel class of Notch inhibitors targeting the transcriptional activation with IC50 of 6 μMol/L.
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Thioredoxin reductas...
Thioredoxin reductase peptide corresponds to residues 53–67 in thioredoxin reductase (TrxR), used in thioredoxin reductase research.Mammalian thioredoxin reductase (TR) catalyzes the reduction of the redox-active disulfide bond of thioredoxin (Trx) and is similar in structure and mechanism to glutathione reductase except for a C-terminal 16-amino acid extension containing a rare vicinal selenylsulfide bond.
