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AZ-Dyrk1B-33

CAS No. 1679330-37-0

AZ-Dyrk1B-33( 3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine )

Catalog No. M26618 CAS No. 1679330-37-0

AZ-Dyrk1B-33 is a potent and selective Dyrk1B kinase inhibitor with an IC50 of 7 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    AZ-Dyrk1B-33
  • Note
    Research use only, not for human use.
  • Brief Description
    AZ-Dyrk1B-33 is a potent and selective Dyrk1B kinase inhibitor with an IC50 of 7 nM.
  • Description
    AZ-Dyrk1B-33 is a potent and selective Dyrk1B kinase inhibitor with an IC50 of 7 nM.(In Vitro):Administration of AZ-Dyrk1B-33 shows inhibition of phosphorylation of Dyrk pS421 in cells with an IC50 of 0.192 μM and no effect in sensitization.
  • In Vitro
    AZ-Dyrk1B-33 shows inhibition of phosphorylation of Dyrk pS421 in cells with an IC50 of 0.192 μM.AZ-Dyrk1B-33 shows no effect in sensitization.
  • In Vivo
    ——
  • Synonyms
    3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    CYP73A
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1679330-37-0
  • Formula Weight
    300.365
  • Molecular Formula
    C19H16N4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (416.17 mM)
  • SMILES
    Cc1nccc(n1)-c1cn(Cc2ccccc2)c2cnccc12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.1. Schalk M, et al, Werck-Reichhart D. Piperonylic acid, a selective, mechanism-based inactivator of the trans-cinnamate 4-hydroxylase: A new tool to control the flux of metabolites in the phenylpropanoid pathway. Plant Physiol. 1998;118(1):209‐218.
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