AVN-322
CAS No. 1194574-68-9
AVN-322 ( AVN322 )
Catalog No. M10684 CAS No. 1194574-68-9
A highly selective, potent, BBB penetrant and orally bioavailable 5-HT6R antagonist for the treatment of neurological disorders such as AD and schizophrenia.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 873 | Get Quote |
|
50MG | 1782 | Get Quote |
|
100MG | 2250 | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameAVN-322
-
NoteResearch use only, not for human use.
-
Brief DescriptionA highly selective, potent, BBB penetrant and orally bioavailable 5-HT6R antagonist for the treatment of neurological disorders such as AD and schizophrenia.
-
DescriptionA highly selective, potent, BBB penetrant and orally bioavailable 5-HT6R antagonist for the treatment of neurological disorders such as AD and schizophrenia; significantly restores both scopolamine- and MK-801-induced cognitive dysfunction and demonstrates antipsychotic potential.Alzheimer Disease Phase 2 Clinical
-
SynonymsAVN322
-
PathwayEndocrinology/Hormones
-
Target5-HT Receptor
-
Recptor5-HT Receptor
-
Research AreaNeurological Disease
-
IndicationAlzheimer Disease
Chemical Information
-
CAS Number1194574-68-9
-
Formula Weight393.89
-
Molecular FormulaC17H20ClN5O2S
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=S(C1=C2N=CC(CN(C)CC3)=C3N2N=C1NC)(C4=CC=CC=C4)=O.[H]Cl
-
Chemical NameN,7-dimethyl-3-(phenylsulfonyl)-6,7,8,9-tetrahydropyrazolo[1,5-a]pyrido[3,4-e]pyrimidin-2-amine hydrochloride
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Ivachtchenko AV, et al. Curr Alzheimer Res. 2017;14(3):268-294.
molnova catalog
related products
-
MM 77 dihydrochlorid...
MM 77 dihydrochloride is an effecitve 5-HT1A receptor postsynaptic antagonist with anxiolytic-like activity.
-
PRX-08066
PRX-08066 is a selective 5-hydroxytryptamine receptor 2B (5-HT2BR, IC50= 3.4 nM) antagonist that induces selective vasodilation of pulmonary arteries.
-
CTEP
CTEP (RO4956371) is a novel, long-acting, orally bioavailable allosteric antagonist of mGlu5 receptor with IC50 of 2.2 nM, shows >1000-fold selectivity over other mGlu receptors.