AVN-211

CAS No. 1173103-84-8

AVN-211 ( AVN211;CD-008-0173 )

Catalog No. M10580 CAS No. 1173103-84-8

AVN-211 (CD-008-0173) is a novel and highly selective 5-HT6 receptor small molecule antagonist with Ki of 2.34 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
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50MG 1782 Get Quote
100MG 2250 Get Quote
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Biological Information

  • Product Name
    AVN-211
  • Note
    Research use only, not for human use.
  • Brief Description
    AVN-211 (CD-008-0173) is a novel and highly selective 5-HT6 receptor small molecule antagonist with Ki of 2.34 nM.
  • Description
    AVN-211 (CD-008-0173) is a novel and highly selective 5-HT6 receptor small molecule antagonist with Ki of 2.34 nM; shows a similar or better anxiolytic efficacy than fenobam, rufinamide, lorazepam, and buspirone in an elevated plus-maze model; significantly delayes or partially halts the progressive decline in memory function associated with AD.Schizophrenia Phase 3 Clinical
  • Synonyms
    AVN211;CD-008-0173
  • Pathway
    Endocrinology/Hormones
  • Target
    5-HT Receptor
  • Recptor
    5-HT Receptor
  • Research Area
    Neurological Disease
  • Indication
    Schizophrenia

Chemical Information

  • CAS Number
    1173103-84-8
  • Formula Weight
    333.42
  • Molecular Formula
    C15H15N3O2S2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=S(C1=C2N=C(C)C=C(C)N2N=C1SC)(C3=CC=CC=C3)=O
  • Chemical Name
    5,7-Dimethyl-2-(methylthio)-3-(phenylsulfonyl)pyrazolo[1,5-a]pyrimidine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Ivachtchenko AV, et al. Mol Pharm. 2016 Mar 7;13(3):945-63.
2. Morozova MA,et al. CNS Spectr. 2014 Aug;19(4):316-23.
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