Cart
sales@molnova.com
Home - Products - Others - Other Targets - ATN-224

ATN-224

CAS No. 649749-10-0

ATN-224 ( Choline tetrathiomolybdate;WTX-101 )

Catalog No. M15467 CAS No. 649749-10-0

ATN-224 (Choline tetrathiomolybdate;WTX-101) is a specific, high-affinity copper binder that inhibits CuZn superoxide dismutase 1 (SOD1) with IC50 of 0.33 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 95 Get Quote
5MG 140 Get Quote
10MG 203 Get Quote
25MG 365 Get Quote
50MG 531 Get Quote
100MG 773 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    ATN-224
  • Note
    Research use only, not for human use.
  • Brief Description
    ATN-224 (Choline tetrathiomolybdate;WTX-101) is a specific, high-affinity copper binder that inhibits CuZn superoxide dismutase 1 (SOD1) with IC50 of 0.33 uM.
  • Description
    ATN-224 (Choline tetrathiomolybdate;WTX-101) is a specific, high-affinity copper binder that inhibits CuZn superoxide dismutase 1 (SOD1) with IC50 of 0.33 uM against purified bovine SOD1, leading to antiangiogenic and antitumour effects; shows no binding to calcium, iron, magnesium, zinc, or manganese ions at 1 mM; inhibits HUVEC proliferation with IC50 1.4 uM; shows a potential therapy against Wilson's disease.Other Indication Phase 3 Clinical
  • Synonyms
    Choline tetrathiomolybdate;WTX-101
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Other Targets
  • Research Area
    Other Indications
  • Indication
    Other Disease

Chemical Information

  • CAS Number
    649749-10-0
  • Formula Weight
    432.54
  • Molecular Formula
    C10H28MoN2O2S4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    S=[Mo]([S-])([S-])=S.OCC[N+](C)(C)C.OCC[N+](C)(C)C
  • Chemical Name
    2-hydroxy-N,N,N-trimethyl-ethanaminium, tetrathioxomolybdate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Juarez JC, et al. Clin Cancer Res. 2006 Aug 15;12(16):4974-82.
2. Doate F, et al. Br J Cancer. 2008 Feb 26;98(4):776-83.
3. Calderon-Aparicio A, et al. Oncotarget. 2015 Oct 6;6(30):29771-81.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • 3-Furoic acid

    3-Furoic acid is an organic acid regularly occurring in the urine of healthy individuals. 3-Furoic acid is also a compound found in honey and honeydew samples.

  • Pseudobufarenogin

    Pseudobufarenogin, a novel anti-tumor compound, suppresses liver cancer growth by inhibiting receptor tyrosine kinase-mediated signaling.

  • Tosufloxacin p-Tolue...

    Tosufloxacin p-Toluenesulfonate Hydrate is a fluoroquinolone antibacterial agent that is used to treat susceptible infections.

Sign In Join Free