ARA290
CAS No. 1208243-50-8
ARA290 ( Cibinetide )
Catalog No. M29894 CAS No. 1208243-50-8
ARA290 is a nonerythropoietic peptide engineered from erythropoietin,, and used for neurological disease treatment.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 447 | In Stock |
|
10MG | 651 | In Stock |
|
25MG | 1017 | In Stock |
|
50MG | 1368 | In Stock |
|
100MG | 1782 | In Stock |
|
200MG | Get Quote | In Stock |
|
500MG | Get Quote | In Stock |
|
Biological Information
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Product NameARA290
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NoteResearch use only, not for human use.
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Brief DescriptionARA290 is a nonerythropoietic peptide engineered from erythropoietin,, and used for neurological disease treatment.
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DescriptionARA290 is a nonerythropoietic peptide engineered from erythropoietin,, and used for neurological disease treatment.(In Vitro):ARA290 enhances the proliferation, migration, and resistance to H2O2-induced apoptosis of endothelial colony-forming cells (ECFCs). ARA290 is an EPO-analog peptide without hematopoietic side-effects but may have neurotrophic and antidepressant effects.(In Vivo):After ECFC transplantation to mice with CLI, a single ARA290 injection enhances the ischemic/non-ischemic ratio of hindlimb blood flow and capillary density after 28 days and the homing of radiolabeled transplanted cells to the ischemic leg 4?h after transplantation. ARA290 (30 μg/kg, s.c.) prevents progressive worsening of glucose control without affecting body weight of rats. ARA290 significantly decreases glucose AUCs in IPGTT in GK rats. Low-dosage ARA290 (35 μg/kg, i.p.) treatment only slightly attenuates the EAE severity in rats. ARA290-treating group (70 μg/kg, i.p.) significantly delays the onset, decreases the neurologic severity and shortens the duration of EAE in a dose-dependent way.
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SynonymsCibinetide
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number1208243-50-8
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Formula Weight1257.3
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Molecular FormulaC51H84N16O21
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 34 mg/mL (27.04 mM)
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SMILES——
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Chemical Name
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
Hache G, et al. ARA290, a Specific Agonist of Erythropoietin/CD131 Heteroreceptor, Improves Circulating Endothelial Progenitors' Angiogenic Potential and Homing Ability. Shock. 2016 Oct;46(4):390-7
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