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ARA-290

CAS No. 1208243-50-8

ARA-290 ( Cibinetide )

Catalog No. M10775 CAS No. 1208243-50-8

ARA-290 (Cibinetide) is a non-erythropoietic erythropoietin (EPO) derivative; specific agonist of erythropoietin/CD131 heteroreceptor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    ARA-290
  • Note
    Research use only, not for human use.
  • Brief Description
    ARA-290 (Cibinetide) is a non-erythropoietic erythropoietin (EPO) derivative; specific agonist of erythropoietin/CD131 heteroreceptor.
  • Description
    ARA-290 (Cibinetide) is a non-erythropoietic erythropoietin (EPO) derivative; specific agonist of erythropoietin/CD131 heteroreceptor; improves insulin release and glucose tolerance in type 2 diabetic GK rats.Diabetes Phase 2 Clinical
  • Synonyms
    Cibinetide
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Other Targets
  • Research Area
    Metabolic Disease
  • Indication
    Diabetes

Chemical Information

  • CAS Number
    1208243-50-8
  • Formula Weight
    1257.31
  • Molecular Formula
    C51H84N16O21
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 34 mg/mL
  • SMILES
    OC[C@@H](C(O)=O)NC([C@H](CO)NC([C@H](CC(N)=O)NC([C@H](CC(C)C)NC([C@H](C)NC([C@H](CCCNC(N)=N)NC([C@H](CCC(O)=O)NC([C@H](CC(C)C)NC([C@H](CCC(N)=O)NC([C@H](CCC(O)=O)NC([C@H](CC1)NC1=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
  • Chemical Name
    L-Serine, 5-oxo-L-prolyl-L-α-glutamyl-L-glutaminyl-L-leucyl-L-α-glutamyl-L-arginyl-L-alanyl-L-leucyl-L-asparaginyl-L-seryl-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. van Rijt WG, et al. J Transl Med. 2013 Jan 9;11:9.
2. Ahmet I, et al. Mol Med. 2011 Mar-Apr;17(3-4):194-200.
3. Muller C, et al. Mol Med. 2015 Dec 29.
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